What is GAMMAGARD LIQUID?

GAMMAGARD LIQUID is a ready-to-use liquid medicine that is given in a vein (intravenously) or under the skin (subcutaneously) to treat primary immunodeficiency (PI) in people 2 years and older.

What is the most important information that I should know about GAMMAGARD LIQUID?

GAMMAGARD LIQUID can cause the following serious reactions: Severe allergic reactions causing difficulty in breathing or skin rashes Decreased kidney function or kidney failure Blood clots in the heart, brain, lungs or elsewhere in the body Severe headache, drowsiness, fever, painful eye movements, or nausea and vomiting Dark colored urine, swelling, fatigue, or difficulty breathing

Who should not use GAMMAGARD LIQUID?

Do not use GAMMAGARD LIQUID if you: Have had a severe allergic reaction to immune globulin or other blood products. Have a condition called selective (or severe) immunoglobulin A (IgA) deficiency.

What should I avoid while taking GAMMAGARD LIQUID?

GAMMAGARD LIQUID can make vaccines (like measles/mumps/rubella or chickenpox vaccines) not work as well for you.Before you get any vaccines, tell your healthcare provider (HCP) that you take GAMMAGARD LIQUID. Tell your HCP if you are pregnant, or plan to become pregnant, or if you are nursing.

What are the possible or reasonably likely side effects of GAMMAGARD LIQUID?

Hives, swelling in the mouth or throat, itching, trouble breathing, wheezing, fainting or dizziness. These could be signs of a serious allergic reaction. Bad headache with nausea, vomiting, stiff neck, fever, and sensitivity to light. These could be signs of irritation and swelling of the lining around your brain. Reduced urination, sudden weight gain, or swelling in your legs. These could be signs of a kidney problem. Pain, swelling, warmth, redness, or a lump in your legs or arms. These could be signs of a blood clot. Brown or red urine, fast heart rate, yellow skin or eyes. These could be signs of a liver or blood problem. Chest pain or trouble breathing, or blue lips or extremities. These could be signs of a serious heart or lung problem.Fever over 100°F. This could be a sign of an infection.

Talking to Your Doctor About GAMMAGARD LIQUID IG Therapy

Talking with your doctor is so important

Your relationship with your doctor goes beyond getting the prescription.

An open dialogue with your doctor means your questions are getting answered, whether you’re just starting therapy or have been on therapy for a while. Your doctor or nurse should know if you have any concerns or any side effects that are bothering you.

If you ever think about taking a break from therapy, you should talk to your doctor first.

They’ll be able to talk to you about what this could mean for you.

Your therapy needs may change throughout treatment.

We get that. You may talk to your doctor about going from monthly to weekly infusions, or vice versa. There are other Takeda therapies to treat PI that you’ll want to know about if you ever decide to make a change.

When it comes to treating primary immunodeficiency (PI), you’ve got options.

GAMMAGARD LIQUID is one of three Takeda therapies to treat PI. Whatever therapy changes you may need, Takeda is here for you. The chart below highlights key details about GAMMAGARD LIQUID (in orange) and the other two medicines to treat PI.

How GAMMAGARD LIQUID compares to other Takeda IG therapies

	GAMMAGARD LIQUID IV	SubQ IG with flexible infusion options	Once-a-month* SubQ IG infusion
Administration options	In a vein	Under the skin	Under the skin with hyaluronidase that helps more IG to be absorbed into the bloodstream
Frequency	Every 3 to 4 weeks	Daily to every 2 weeks	Every 3 to 4 weeks
Average infusion time^†	~2 hours	~1 to 2 hours	~2 hours
Infusion time range^†	~1 to 2 hours	~5 min to 2 hours	~1 to 2 hours
Who administers	Nurse	Yourself or care partner after training by HCP	Nurse or yourself or care partner after training by HCP
Location	Home, healthcare office, hospital, or infusion center	Home, healthcare office, hospital, or infusion center	Home, healthcare office, hospital, or infusion center
		Learn more	Learn more