When you are managing treatment for PI, it's important to keep track of several different factors. For people with PI who are on an Immunoglobulin (Ig) treatment, whether it is given in a vein (intravenously) or under the skin (subcutaneously),1 here are 5 things you should know about your Ig treatment:
Five Things You Should Know About Your Ig Treatment
- Brand: Every IV and SubQ Ig brand is made, processed, and stabilized in a different way. These differences in Ig formulations might make one brand more suitable for you than another.1 Being aware of the brand your healthcare provider has prescribed allows you to make sure it's used for each infusion. Be aware that side effects may occur more frequently in patients receiving Ig for the first time, upon switching brands or if there has been a long interval since the previous infusion. In such cases, your physician may start your infusion at a lower infusion rate and gradually increase the rate as tolerated.1
- Dosage: Your physician may need to adjust your dose to achieve the desired clinical response. Your dosage may also need to be adjusted, as it is based on weight and PI condition, which may vary over time.1
- Rate of infusion: You may find that you respond differently to different rates of infusion. Slowing down the rate of infusion can sometimes reduce side effects.2
- How to keep an infusion log: Tracking your response to brand, dosage, and frequency of infusion can be beneficial to both you and your treatment team. An infusion log helps you keep track of your infusions.1
- Where your Ig treatment comes from: It also helps to know how your Ig treatment (IV or SubQ) brand is processed. To learn more about the Shire manufacturing process and plasma collection, view About Plasma Treatment.
References: 1. Younger MEM, ed. IDF Guide for Nurses: Immunoglobulin Therapy for Primary Immunodeficiency Diseases. 4th ed. Towson, MD: Immune Deficiency Foundation; 2016. 2. Blaese RM, Bonilla FA, Stiehm ER, Younger ME, eds. Patient & Family Handbook for Primary Immunodeficiency Diseases. 5th ed. Towson, MD: Immune Deficiency Foundation; 2013.
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