What is MMN?
MMN is a rare, treatable, but incurable disorder of the immune system which causes muscle weakness that worsens over time.1,2 MMN commonly begins in the finger, thumb, wrist, or lower leg.3,4 It affects the strength in the lower parts of the arms and hands more than the legs, usually without affecting the touch sensation.1 MMN usually causes weakness in one side of the body (asymmetrical).4
People with MMN may have symptoms that include:
- Difficulty gripping objects2
- Spasms or cramps usually in one arm or leg4
- Wrist drop (when the wrist cannot be extended)2,5
- Foot drop (difficulty lifting the front part of the foot)2,5
- Increased muscle weakness in response to cold temperatures4
- GAMMAGARD LIQUID [Immune Globulin Infusion (Human)] 10% [Prescribing Information]. Westlake Village, CA: Baxalta US Inc.
- Katirji B, Koontz D. Disorders of peripheral nerves. In: Daroff RB, Fenichel GM, Jankovic J, Mazziotta JC, eds. Bradley's Neurology in Clinical Practice. 6th ed. Philadelphia, PA: Elsevier Saunders; 2012:1915-2015.
- Slee M, Selvan A, Donaghy M. Multifocal motor neuropathy: the diagnostic spectrum and response to treatment. Neurology. 2007;69(17):1680-1687.
- Vlam L, van der Pol WL, Cats EA, et al. Multifocal motor neuropathy: diagnosis, pathogenesis and treatment strategies. Nat Rev Neurol. 2012;8(1):48-58.
- Taber's Medical Dictionary Online. 23rd ed. https://www.tabers.com/tabersonline/. Accessed May 18, 2017.
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