Treating PI With Immunoglobulin (Ig) Infusion
Ig treatment is one option for treating primary immunodeficiency (PI) that is caused by impaired antibody production. However, it is not appropriate for everyone. Talk to your doctor about what treatment may be best for you.
What Is Ig?
Ig—also referred to as IgG, immune globulin, and immunoglobulin—is one type of antibody normally made by the body's immune system. Others include IgM, IgE, IgD and IgA. The IgG antibodies help fight off bacteria and viruses that cause infections that can make you sick. If you have PI, your body may not be making enough antibodies, or some of the antibodies it's making don't work properly.1 That's why you get sick so often.
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What Is Ig Treatment?
Ig treatment temporarily replaces some of the antibodies that your body isn't making on its own or that don't work properly.1 The goal of this treatment is to keep enough antibodies in your blood so your body can help to fight off bacteria and viruses, and help keep you from getting sick so often.1
Where Ig Treatment Comes From
Human plasma donations are the first step in producing Ig treatments. A donor's plasma is put through a rigorous series of tests, including screening for specific infectious diseases and measurement of protein levels and hematocrit to make sure they are both in an acceptable range for donation. Once it is determined safe for use, the plasma is sent to a processing plant where it is processed into numerous plasma based treatments, including Ig treatment.1
Learn more about Shire's Immunoglobulin (Ig) treatment options.
Reference: 1. Blaese RM, Bonilla FA, Stiehm ER, Younger ME, eds. Patient & Family Handbook for Primary Immunodeficiency Diseases. 5th ed. Towson, MD: Immune Deficiency Foundation; 2013.
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