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Choosing What's Best for You: IV or SubQ Administration

With Ig treatment, your doctor and you can choose IV or SubQ administration for the treatment of PI. Your choice will shape your infusion experience, including where and how often you receive treatment and whether your healthcare professional administers your infusion.

There have been no head-to-head clinical studies conducted comparing these products. Please talk to your doctor about the appropriate treatment for you.

GAMMAGARD LIQUID -- IV or SubQ Administration

Indicated for patients two years of age and older with primary immunodeficiency

Intravenous (IV)1,2

Conventional SubQ1,2

Infused directly into the bloodstream through a vein Infused under the skin in the fatty tissues of the abdomen, thighs, upper arm, or lower back
Administered once every 3 to 4 weeks Administered once a week
Dose given in 1 site Dose given in multiple sites
Administration requires a healthcare professional Can be self-administered after patient is trained by a healthcare professional
Infused at hospital, clinic, or home with nurse present Infused at home after training

For more information regarding all Shire IG products please visit Shire.com and MyIgSource.com


To learn more about PI and treatment with GAMMAGARD LIQUID treatment, both IV and SubQ, you can download the brochure from our Additional Resources page.


Doctor Discussion Guide

Our discussion guide, “GAMMAGARD LIQUID — IV or SubQ Administration: Which is right for you?” can help you discuss your options with your healthcare provider.

 Download Doctor Discussion Guide

 Download Full Prescribing Information

References: 1. Blaese RM, Bonilla FA, Stiehm ER, Younger ME, eds. Patient & Family Handbook for Primary Immunodeficiency Diseases. 5th ed. Towson, MD: Immune Deficiency Foundation; 2013. 2. GAMMAGARD LIQUID [Immune Globulin Infusion (Human)] 10% [package insert]. Westlake Village, CA: Baxter Healthcare Corporation; September 2013.


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Terms and Conditions

Patient instructions

  1. By using this coupon, you are certifying that:
  2. 1) You meet the eligibility criteria and have read and agree to the terms and conditions of this manufacturer coupon program;
  3. 2) You will not, at any time, submit any costs for the product dispensed pursuant to this coupon to any government healthcare program for reimbursement;
  4. 3) You are permitting your personal information, including name, address, phone number, email address, and information related to health insurance and treatment, to be shared with Shire and companies working with Shire for the purpose of administering this program; and
  5. 4) You will notify your health insurance provider or other third-party payer of the use of this coupon if required to do so.
  6. If your insurance situation changes it is your responsibility to notify Shire's MyIgCoPayCard program.
  7. For questions about this program, patients and caregivers can call MyIgSource at (855) 250-5111.

Pharmacy instructions

  1. By submitting a claim for reimbursement pursuant to this manufacturer coupon program, the Pharmacy represents and warrants that:
  2. 1) It has dispensed GAMMAGARD LIQUID treatment to an eligible patient and in accordance with the terms and conditions of this program and the accompanying prescription;
  3. 2) Its participation in this program is consistent with all applicable laws and any obligations, including its contract with the applicable payer;
  4. 3) If the patient's insurance situation changes, it will notify Shire immediately by contacting the MyIgCoPayCard program;
  5. 4) It will report coupon assistance received to payers if so required; and
  6. 5) The entire benefit amount received will go to eligible expenses and it will not retain any portion of the benefit as payment to it for administration or ineligible expenses.
  7. For questions regarding processing, claim transmission, patient eligibility, or other issues, pharmacists can call the MyIgCoPayCard program directly at (855) 217-1615.